this post was submitted on 09 Nov 2025
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[–] tias@discuss.tchncs.de 107 points 1 day ago* (last edited 23 hours ago) (7 children)

The trick is to time the cocaine and crystal meth ingestion so that they peak at the same time that you orgasm, leading to an 80% * 300% * 1400% = ~~7460%~~ 10700% dopamine increase.

[–] Kyrgizion@lemmy.world 66 points 1 day ago (1 children)

Your permanently burned out synapses will thank you for the vacation.

[–] tomiant@piefed.social 28 points 1 day ago

They weren't doing much for me anyway

[–] adhocfungus@midwest.social 46 points 1 day ago (1 children)

I heard the dev didn't intend for those to stack and it's nerfed in the next patch.

[–] arrow74@lemmy.zip 14 points 1 day ago (1 children)

I heard there's a flaw in the code meaning they cannot patch the old consumables and have to release a new version instead.

It's unclear if the pre-patch consumables will be usable after the patch or if they'll simply be deleted.

Imo the best move is to collect and sell to the hoarders. Not worth the risk of losing all that time I'd rather be able to buy the new stuff even if it doesn't stack

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[–] lime@feddit.nu 26 points 1 day ago (2 children)

if you cum, snort, and puff at the same time, your body goes into recovery mode

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[–] taiyang@lemmy.world 13 points 1 day ago

Careful, some of us on older hardware have a bug where we overflow and crash the system. My second cousin bricked his system just by stacking the last two.

[–] Zozano@aussie.zone 10 points 22 hours ago (1 children)
[–] MojoMcJojo@lemmy.world 5 points 21 hours ago (1 children)

I experienced a 'mild' instance of this. No f'ing thank you would I ever ever want to go through that again.

[–] monotremata@lemmy.ca 4 points 20 hours ago

Same. Uggh. It was a bit like a fever, but so much worse. I was absolutely freezing and couldn't stop shaking and sweating, but I also couldn't really manage to distract myself with anything because my brain didn't work, so I just had to lay there and wait. There was also this overwhelming, crushing ringing sound and a feeling like old analog TV static, along with a splitting headache. Thankfully my family were around, of whom I was dimly aware, so I could tell that time was probably passing, and I could kind of gauge that I probably wasn't getting worse, or they'd take me to a hospital or something. That's about the limit of what I was aware of, though. It just felt like it went on a really long time. I suspect in reality it didn't last more than a few hours. I should ask; I'm sure one of them has a clearer memory of that aspect than I do.

[–] YoSoySnekBoi@kbin.earth 10 points 1 day ago (2 children)

I've been running calculations for the last 10 minutes trying to figure out where tf you got 7460% from lmao

[–] ryedaft@sh.itjust.works 6 points 1 day ago

Yeah, I'm getting 10700%

[–] tias@discuss.tchncs.de 3 points 1 day ago* (last edited 1 day ago)

Yeah I made a mistake. The proper calculation for an increase by 80%, then 300%, then 1400% should be

x * ((1+0.80) * (1+3.00) * (1+14.00) - 1) =

x*(1.8 * 4 * 15 - 1) = x*107 = 10700%

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[–] biggerbogboy@sh.itjust.works 38 points 1 day ago (4 children)

Sounds like a meth-cocaine orgasm is optimal then!

[–] lemmydividebyzero@reddthat.com 22 points 1 day ago (1 children)
[–] biggerbogboy@sh.itjust.works 11 points 1 day ago (1 children)
[–] crank0271@lemmy.world 6 points 1 day ago (1 children)

It's not on the chart but can we multiply by skydiving?

[–] tomiant@piefed.social 4 points 1 day ago

We don't mix toys.

[–] tomiant@piefed.social 8 points 1 day ago

Meth and coke? Good luck with that ejaculation

[–] Matticus@lemmy.world 4 points 1 day ago

Doctors hate this one simple trick

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[–] gigastasio@sh.itjust.works 28 points 1 day ago (5 children)

The arrow on the y axis implies that there something beyond meth that does even better… 🤔

[–] Agent641@lemmy.world 28 points 1 day ago (1 children)

The feeling you get when you peel the protective film off the door of a brand new refrigerator

[–] crank0271@lemmy.world 11 points 1 day ago (2 children)

And then replace it with a black garbage bag because it's a Samsung fridge

[–] tomiant@piefed.social 4 points 1 day ago

It's a dalek?

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[–] cyrano@piefed.social 13 points 1 day ago

The dragon 🐉 is at the end. That’s why you chase it

[–] tomiant@piefed.social 3 points 1 day ago (1 children)
[–] Rai@lemmy.dbzer0.com 4 points 23 hours ago

Having done all of these, DMT does not have the same kind of dopamine release. It is, however, the far most interesting of all of these. But definitely not something I’m ready to casually do at a party, unlike a couple bumps of fine Peruvian nasal fuel.

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[–] daannii@lemmy.world 27 points 21 hours ago* (last edited 21 hours ago)

These drugs release endorphins not dopamine.

Dopamine is not a feel-good neurotransmitter.

It's widely misunderstood and misapplied.

Dopamine in the brain is actually more tied into motor control and function.

A loss of dopamine producing neurons causes Parkinson's. Interestingly, giving parkinson patients drugs to boost dopamine gives them schizophrenia like symptoms. Dopamine is not related to the reward feeling. Please stop pushing this narrative. It's probably one of the most annoying misunderstanding of modern neuroscience in the last few years.

Dopamine is implicated in part of the reward pathway but it is not the reward feeling.

Instead it is part of conditioning expectations for drug use related to behaviors that get the drug.

It's kind of complicated but again. It 100% is not a feel-good neurotransmitter.

It is not what makes you enjoy anything.

You are getting confused with endorphins.

And euphoric effects of drugs. Which are independent from dopamine.

[–] JasonDJ@lemmy.zip 18 points 1 day ago (1 children)

Have I been getting really bad coke?

[–] Rai@lemmy.dbzer0.com 12 points 22 hours ago (1 children)

Having had oodles of bad to mediocre coke in my days and then having 90+% pure (tested myself) I honestly think this graph is misleading, and coke is waaaaay higher.

The problem is, meth dumps your serotonin and feels good by itself, while coke requires you to be doing something that dumps your sweet brain chems to really feel good-good. I don’t know the science behind it but it’s been explained to me. Doing coke and sitting around watching a show is meh. Doing blow and playing a stimulating video game or doing a project that feels good or talking your partner’s ear off (and they yours in return) about ridiculous shit feels incredible.

But yeah. If you need to do a couple lines of coke to really feel it, it’s not good. If you’re getting zooted off a couple bumps, that’s the good stuff.

[–] miked@piefed.social 4 points 19 hours ago (1 children)
[–] Rai@lemmy.dbzer0.com 6 points 18 hours ago (4 children)

Hahaha I had done it a few times during my rave phase but I was almost always disappointed. Like, you gotta do so much of it that it clogs your nose and it goes away so quickly! Then randomly an acquaintance of mine maaaany years later told me they dabbled (understatement) and I learned that almost all coke is complete garbage. A couple bumps had me zooted for like an hour. Remember kids, if it’s already a powder when it comes to you, it’s been stepped on. If you’re getting a shiny chunk that’s almost gummy-feeling, you’re in for a treat.

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[–] tomiant@piefed.social 16 points 1 day ago (1 children)

Crystal meth cured my autism

[–] naught@sh.itjust.works 14 points 1 day ago

i take a handful of tylenol with my meth to maintain autistic homeostasis

[–] Cevilia@lemmy.blahaj.zone 14 points 11 hours ago

So you're telling me that four orgasms is roughly equivalent to doing cocaine?

Hold that thought.

[–] Tkpro@lemmy.world 14 points 21 hours ago (1 children)
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[–] starman2112@sh.itjust.works 12 points 18 hours ago

girlfriend called... DECLINE! busy whore!

busy with my METH

[–] bitwolf@sh.itjust.works 7 points 20 hours ago* (last edited 20 hours ago) (2 children)

Orgasm is 80%, what's 100%?

[–] BananaTrifleViolin@lemmy.world 16 points 20 hours ago (1 children)

Probably 80% increase from baseline. 0% is that background existential dread we all feel.

[–] humorlessrepost@lemmy.world 5 points 19 hours ago

Right guys? Right?

[–] SCmSTR@lemmy.blahaj.zone 13 points 18 hours ago

Orgasm plus cuddles

[–] InvalidName2@lemmy.zip 5 points 22 hours ago

Doing crystal meth will lift you up until you break.

[–] ImgurRefugee114@reddthat.com 5 points 1 day ago (2 children)
[–] TurboToad@lemmy.world 9 points 1 day ago

Dopamine release

[–] dabaldeagul@feddit.nl 3 points 21 hours ago (2 children)

Your baseline dopamine levels. So 80% more = 1.8x your normal dopamine.

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[–] Asetru@feddit.org 4 points 1 day ago (2 children)

So an orgasm will reduce the dopamine level to only 80% of where it's supposed to be? Like you come and immediately just feel a little weird and disappointed?

Like, I get it. It's just nice to see it in writing.

[–] LodeMike@lemmy.today 12 points 1 day ago

No. 80% increase.

[–] yermaw@sh.itjust.works 4 points 23 hours ago

Its that moment when you sober up and see what's on your screen. Cant alt+f4 fast enough.

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