this post was submitted on 07 Jul 2025
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Gotcha, yeah and thanks once again for the discussion. What I’m looking for basically is just evidence for the claim posted above us, specifically that “it is a fact that weight loss results in lifelong ravenous hunger due to fat cell signaling”
Scientists all the time come out with reviews and proposals that ultimately fizzle out without supporting evidence. So before I am able to believe any specific claims I need to see that it’s an actual scientific finding rather than just something tentative that has caught headlines (like I said, it happens all the time).
Since you like reading studies in general, for your own amusement I would suggest investigating the claim “cooking rice with coconut oil, then leaving it in the fridge overnight, will reduce the calories absorbed by your body by half!”
It’s a total and blatant piece of misinformation based on a chain of bad news reports made about a study that claimed something totally different, and was subsequently never confirmed. Yet I have met people in real life who swore by the method (even though they struggled to lose weight regardless of this supposed calorie cutting “hack”).
The weight loss space in general is totally flooded with this type of misinfo which is why I get so particular about it. Thank you again!
In my reading the the literature there is nothing to support this "fat cells make you hungry" theory.
At best there is an association between fat people and fat cell population, but given hyperplasia is more common in people of european descent its not a causal connection. Plus this theory doesn't account for fat people from hypertrophic populations (asians).
That reminds me of that peanut butter, professor nutz. They claim that due to adding certain fibers to their peanut butter, it reduces the digested calories from around 200 calories to 36 calories. They took a concept that exists, fiber-fat bonding, and an in house pilot study of 6 people over 2 weeks, and use that to market this as some kind of miracle peanut butter. Is it technically possible that somebody eating that peanut butter only digests 36 calories per serving? Yes, but it's (to me) very unlikely and changes person to person (which they admit).