this post was submitted on 05 Jun 2025
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Technology
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Opening someone's head to pretend to have done something sounds very unnecessarily cruel and stupid.
Thats their point. How do you test placebo effect for a surgical operation?
Either way, that is a pretty massive digression from the article, which is about medications. Apparently more people are dying on average from recently approved drugs than are dying from all illegal drug use combined. And the examples are not for extremely rare medications
We basically are already there now, it seems
Fair point, but a lot of the article talks about how many studies aren't meeting all four pillars of clinical trial design - that's where my issue comes in, I think reporting that X% of trials do not meet all pillars is a bad metric.
And, not all medications these days are pills or IV infusions - some medications and treatments, which are governed by the FDA, are more invasive and more complicated.
You can do single-blind. You do prep, anesthetize, then open the card that decides if the surgery continues, or if the patient is simply awakened at the expected time.
You can also do it for surgeries that use locals, but then the surgical staff has to do a lot of miming/acting instead of actual cutting.
Medlife Crisis did a couple of Placebo effect videos, and mentioned that he participated in a single-blind stent study.
I don't know how you'd do double-blind.
That a great take.
Double blind could be a different team comes In and either does the surgery or fakes it. And this team also does or Fakes the after care.
This team is never to communicate with patient or normal staff.