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Imagine every day, your muscles get just a little bit weaker. Maybe you can't open a container you used to be able to. Or you find you can't lift your arms high enough to shampoo your hair anymore. No matter how much you try to exercise, it never helps. Pain sets in due to incredible stiffness. Your fingers start to curl up until they are nigh unusable. Entire limbs become gnarled.
Eventually you lose the ability to walk. Then speak. Then eat. And finally, even your breathing muscles become so weak and paralyzed that you constantly aspirate due to your inability to cough. Recurrent infections set in. Then you die of respiratory failure.
And the entire time, people shame you for being lazy and not exercising. They blame your diet, your screen-time, and gleerfuly take joy in your "just" suffering.
EDIT: You then find an actual cure, and are desperately using it. You can barely keep up, then someone yanks it out of your hand "stop using that! It's making you worse!".
Having no other choice, you slowly wither alive.
I watched my father go through that. MND is horrible for the person and everyone around them.