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Having rabies and not knowing it until it's too late
Having it at all is already too late.
Only once you have symptoms is it too late.
You can have it for years before symptoms appear, though the average is two months. If you get vaccinated before then, you're good.
some people have reported getting numbess around the bite wound like days after, which is a sign of the rabies already infecting the nerves around the bite area. there was a house episode like this, where foreman dint realize house has stabbed his bite wound with a needle.