Thanks for the added insights! I haven't used it myself, so appreciated.
Linux has a second, similar "compressed memory" feature called zswap. This guy has used both, and thinks that if someone is using a system with NVMe, that zswap is preferable.
https://linuxblog.io/zswap-better-than-zram/
Based on his take, zram is probably a better choice for that rotational-disk Celeron, but if you're running Cities: Skylines on newer hardware, I'm wondering if zswap might be more advantageous.
I can only imagine that maybe all the mentions of "brain" in this article is something in common with Vice's recreational drug articles.