I recommend reading the wabbitwiki to get all the best information.
Rabbits are social, but they can also be territorial. It's typically recommend to keep a bonded pair of rabbits. One male and one female.
It's best to keep rabbits indoors, with at least 4 feet by 4 feet of play area. Typically people use portable dog pens. We used to do this, but once our rabbits got settled in their space, we removed the pens. Now they can go wherever they want, but they choose never to leave thier room.
They are litter box trained. It's a different kind of litter than cat litter. We use a layer of compressed pine pellets topped with hay.
Rabbits pee and poop in the litter box, but they will always poop a little bit outside the box. The nice thing is, rabbit poops are dry little balls that don't really smell, so we just vacuum it up.
I really like our rabbits. The hardest thing about them is all the bad information. For example, a pet store will sell you a hutch or cage which is much too small. They also will charge you way too much for hay and sell you unhealthy feed pellets. The wabbitwiki is a valuable resource.
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I couldn't resist sending a picture. This is Ciel, one of our three rabbits. He lives by himself in the main room because he hates other rabbits, but he loves humans.