this post was submitted on 18 Nov 2025
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[–] Lemmyoutofhere@lemmy.ca 27 points 2 days ago (1 children)

"Only 1h after the injection we observed a reduction of 50-60% in Aβ amount inside the brain"

Wow.

[–] frongt@lemmy.zip 8 points 2 days ago (2 children)

Meanwhile, OP posted an article at the same time saying that amyloid proteins don't actually seem to be related to Alzheimer's: https://www.sciencedaily.com/releases/2025/11/251111005944.htm

[–] AbouBenAdhem@lemmy.world 26 points 2 days ago

That article reports that a drug targeted at clearing amyloid proteins didn’t suffice to restore the brain’s waste-clearing functionality; this article reports that a drug targeted at repairing the blood-brain barrier does restore waste-clearing functionality (including amyloid proteins). So they’re not completely contradictory.

[–] Lemmyoutofhere@lemmy.ca 6 points 2 days ago

Different pathways.

[–] SolidShake@lemmy.world 18 points 2 days ago (2 children)

If this goes to human trials and works and then gets approved for every patient I can only imagine the hundreds of thousands of debt this will put people and their families in. It's awesome news, but the reality of it sucks

[–] AbouBenAdhem@lemmy.world 23 points 2 days ago

It looks like the research was done by academic and government-sponsored institutions in Spain and China, so hopefully it won’t just become a profit-making tool for the biotech industry.

[–] Fredselfish@lemmy.world 6 points 2 days ago (1 children)

This will be given to people like Trump. Us poors will not be given this drug.

[–] zout@fedia.io 6 points 2 days ago

Let's give it to Trump tomorrow, before his mind is gone so far that he can't be held accountable anymore!

[–] jordanlund@lemmy.world 6 points 2 days ago

So, wait, we figured out how to give mice alzheimers and then cure it? 🤔

[–] AmidFuror@fedia.io 3 points 2 days ago

I can't wait to share this news with my friend Charlie. Should I bring flowers?

[–] spittingimage@lemmy.world 2 points 2 days ago

There's hope for me yet.

[–] FauxPseudo@lemmy.world 2 points 2 days ago* (last edited 1 day ago) (1 children)

Mice lie. Monkeys exaggerate. Ferrets are weasels.

[–] MalReynolds@piefed.social 4 points 1 day ago (1 children)

Not nice Lie Mice lie.

I normally don't bother with typos, but this one changes meaning significantly, for those not in the know it's a saying in biological / biomedical science about the relevance of animal testing results to humans, although I'm unfamiliar with the ferrets part, but it's cool.

Mice lie and Monkeys exaggerate. - On the use of non-human primates in HIV research, Stephen B Weiner PhD.