Selfhosted
A place to share alternatives to popular online services that can be self-hosted without giving up privacy or locking you into a service you don't control.
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I do not have any RAM to share, sorry.
An economics simulation in Python needing 200+GB of RAM sounds preventable.
In your friend's shoes, I might start asking for pointers over on the programming.dev Lemmy.
As others have said, a rewrite in a faster language like C or goLang could help - but my guess is there's also ways to cut that memory need way down, while still using Python.